Pipeline

Lenabasum

Multi-system Inflammatory

Systemic Sclerosis

Preclinical Phase 1 Phase 2 Phase 3 Launch
Preclinical Phase complete
Phase 1 Phase complete
Phase 2 Phase complete
Phase 3 Phase in progress
Launch Phase not started

Targeting 2021 launch

Multi-system Inflammatory

Dermatomyositis

Preclinical Phase 1 Phase 2 Phase 3 Launch
Preclinical Phase complete
Phase 1 Phase complete
Phase 2 Phase complete
Phase 3 Phase in progress
Launch Phase not started

Multi-system Inflammatory

Systemic Lupus Erythematosus

Preclinical Phase 1 Phase 2 Phase 3 Launch
Preclinical Phase complete
Phase 1 Phase complete
Phase 2 Phase in progress
Phase 3 Phase not started
Launch Phase not started
Preclinical Phase 1 Phase 2 Phase 3 Launch
Preclinical Phase complete
Phase 1 Phase complete
Phase 2 Phase in progress
Phase 3 Phase not started
Launch Phase not started

CRB-4001

Preclinical Phase 1 Phase 2 Phase 3 Launch
Preclinical Phase in progress
Phase 1 Phase not started
Phase 2 Phase not started
Phase 3 Phase not started
Launch Phase not started

Scheduled to Enter Phase 1 in 2019, NIH Committed to Funding Phase 2 Study.

Preclinical library (more than 600 compounds)

Goal: 1-2 new Phase 1 programs per year starting in 2020

Preclinical Phase 1 Phase 2 Phase 3 Launch
Preclinical Phase in progress
Phase 1 Phase not started
Phase 2 Phase not started
Phase 3 Phase not started
Launch Phase not started